Complement component 1q: Difference between revisions

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==Function==
[[Image:Complement pathway.svg|thumb|270px|rightleft|The classical and alternative complement pathways.]]
It is assumed that the globular ends are the sites for multivalent attachment to the complement fixing sites in immune complexed immunoglobulin. Patients suffering from Lupus erythematosus often have deficient expression of C1q. Genetic deficiency of C1q is extremely rare (approximately 75 known cases) although the majority (>90%) of those suffer from [[Systemic lupus erythematosus|SLE]]. C1q may also play a central role in the aging of cells.<ref name="Secret of ageing found: Japanese scientists pave way to everlasting life">{{cite web|title=Secret of ageing found: Japanese scientists pave way to everlasting life|url=http://www.rt.com/news/japan-scientists-stop-ageing-461/|work=Russia Today|publisher=Russia Today|accessdate=10 June 2012}}</ref>