Revision as of 14:22, 2 April 2016 edit Rod57 (talk \| contribs) Autopatrolled, Extended confirmed users, Pending changes reviewers 33,163 edits m →Function: try image on left ← Previous edit		Revision as of 14:45, 2 April 2016 edit undo Rod57 (talk \| contribs) Autopatrolled, Extended confirmed users, Pending changes reviewers 33,163 edits →Function: C1-complex, the Next edit →
Line 77: It is assumed that the globular ends are the sites for multivalent attachment to the complement fixing sites in immune complexed immunoglobulin. Patients suffering from Lupus erythematosus often have deficient expression of C1q. Genetic deficiency of C1q is extremely rare (approximately 75 known cases) although the majority (>90%) of those suffer from [[Systemic lupus erythematosus\|SLE]]. C1q may also play a central role in the aging of cells.<ref name="Secret of ageing found: Japanese scientists pave way to everlasting life">{{cite web\|title=Secret of ageing found: Japanese scientists pave way to everlasting life\|url=http://www.rt.com/news/japan-scientists-stop-ageing-461/\|work=Russia Today\|publisher=Russia Today\|accessdate=10 June 2012}}</ref> C1q associates with C1r and C1s in order to yield the [[C1-complex]], the first component of the serum [[complement system]]. Deficiency of C1q has been associated with [[lupus erythematosus]] and [[glomerulonephritis]].<ref name="entrez ciqa"/> ==References==

Complement component 1q: Difference between revisions