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Deleted "Bioinformatics", bioinformatics is used to generate the data for interpretation, but otherwise has nothing to do the a SNP array as described here, so a Computational (whatever) expert is not needed for this article |
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The basic principles of SNP array are the same as the DNA microarray. These are the convergence of [[DNA hybridization]], [[fluorescence microscope|fluorescence microscopy]], and solid surface DNA capture. The three mandatory components of the SNP arrays are:
# An array containing immobilized [[allele-specific oligonucleotide]] (ASO) probes.
# Fragmented [[nucleic acid]] sequences of target,
# A detection system that records and interprets the [[DNA-DNA hybridization|hybridization]] signal.
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