Human Protein Reference Database: Difference between revisions

Revision as of 02:59, 30 March 2016

Revision as of 21:24, 26 December 2016

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Highlights of HPRD as follows:

* From 10,000 protein–protein interactions (PPIs) annotated for 3,000 proteins in 2003, HPRD has grown to over 36,500 unique PPIs annotated for 25,000 proteins including 6,360 isoforms by the end of 2007.<ref>{{cite journal | author = Mathivanan S. | year = | title = An evaluation of human protein–protein interaction data in the public ___domain | url = | journal = BMC Bioinformatics | volume = 2006 | issue = 7| page = S19 | doi=10.1186/1471-2105-7-s5-s19|display-authors=etal | pmid=17254303 | pmc=1764475}}</ref>

* More than 50% of molecules annotated in HPRD have at least one PPI and 10% have more than 10 PPIs.

* Experiments for PPIs are broadly grouped into three categories namely in vitro, in vivo and [[yeast two hybrid]] (Y2H). Sixty percent of PPIs annotated in HPRD are supported by a single experiment whereas 26% of them are found to have two of the three experimental methods annotated.