Transporter Classification Database: Difference between revisions

Revision as of 17:53, 16 December 2016

Revision as of 11:33, 31 December 2016

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The '''Transporter Classification Database''' (or '''TCDB''') is an [[International Union of Biochemistry and Molecular Biology]] (IUBMB)-approved classification system for [[membrane transport protein]]s, including [[ion channel]]s.<ref>{{cite journal|last1=Saier|first1=Milton H.|last2=Reddy|first2=Vamsee S.|last3=Tamang|first3=Dorjee G.|last4=Västermark|first4=Åke|title=The Transporter Classification Database|journal=Nucleic Acids Research|date=January 2014|volume=42|issue=D1|pages=D251–D258|doi=10.1093/nar/gkt1097|url=http://nar.oxfordjournals.org/content/42/D1/D251|accessdate=1 March 2016}}</ref><ref>{{cite journal|last1=Saier|first1=M. H.|last2=Yen|first2=M. R.|last3=Noto|first3=K.|last4=Tamang|first4=D. G.|last5=Elkan|first5=C.|title=The Transporter Classification Database: recent advances|journal=Nucleic Acids Research|date=1 January 2009|volume=37|issue=Database|pages=D274–D278|doi=10.1093/nar/gkn862|url=http://nar.oxfordjournals.org/content/37/suppl_1/D274|accessdate=1 March 2016|pmid=19022853|pmc=2686586}}</ref><ref>{{cite journal|last1=Saier|first1=M. H.|last2=Tran|first2=C. V.|last3=Barabote|first3=R. D.|title=TCDB: the Transporter Classification Database for membrane transport protein analyses and information|journal=Nucleic Acids Research|date=1 January 2006|volume=34|issue=90001|pages=D181–D186|doi=10.1093/nar/gkj001|url=http://nar.oxfordjournals.org/content/34/suppl_1/D181|accessdate=1 March 2016|pmid=16381841|pmc=1334385}}</ref>

==Classification==

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* 1.A.34 [[Bacillus gap junction-like channel-forming complex family|''Bacillus'' gap junction-like channel-forming complex family]]

* 1.A.35 [[CorA metal ion transporter|CorA metal ion transporter family]]

* 1.A.36 [[Chloride_channelChloride channel#CLIC_familyCLIC family|Intracellular chloride channel family]]

* 1.A.37 [[The CD20 Ca2+ channel family|CD20 Ca²⁺ channel family]]

* 1.A.38 [[The Golgi pH regulator family|Golgi pH regulator family]]

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====2.A Porters ([[uniporter]]s, [[symporter]]s, [[antiporter]]s)====

{{see also|Amino acid transporter}}

*2.A.1 [[Major facilitator superfamily|Major Facilitator superfamily]] (MFS), see also [[Lactose permease]], [[Phosphate permease]] and [[Glucose transporter]]

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*2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR (TonB) Family of Auxiliary Proteins for Energization of Outer Membrane Receptor (OMR)-mediated Active Transport

===3. [[Primary active transport|Primary active transporters]]ers===

====3.A. P-P-bond hydrolysis-driven transporters====