Reliability theory of aging and longevity: Difference between revisions

Revision as of 00:04, 29 November 2017

Revision as of 00:08, 29 November 2017

Line 5:

{{use list-defined references|date=September 2015}}

The '''reliability theory of aging''' is an attempt to apply the principles of [[reliability theory]] to create a [[mathematical model]] of [[agingsenescence]]. The theory was published in Russian by [[Leonid A. Gavrilov]] and Natalia S. Gavrilova as ''Biologiia prodolzhitelʹnosti zhizni'' in 1986, and in English translation as ''The Biology of Life Span: A Quantitative Approach'' in 1991.{{r|gav|rayl}}

One of the models suggested in the book is based on an analogy with the reliability theory. The underlying [[hypothesis]] is based on the (previously suggested) premise that humans are born in a highly defective state. This is then made worse by environmental and mutational damage; exceptionally high [[Redundancy (engineering)|redundancy]] due to the extremely high number of low-reliable components (e.., [[cell (biology)|cell]]s) allows the organism to survive for a while.{{r|ieee}}<ref name=gg2001/>