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The '''complement component 1q''' (or simply '''C1q''') is a [[protein complex]] involved in the [[complement system]], which is part of the [[innate immune system]]. C1q together with [[C1r]] and [[C1s]] form the [[C1 complex]].
[[Antibody|Antibodies]] of the [[adaptive immune system]] can bind [[antigen]], forming an [[antigen-antibody complex]]. When C1q binds antigen-antibody complexes, the [[C1 complex]] becomes activated. Activation of the C1 complex intitiates the [[classical complement pathway]] of the complement system. The antibodies [[IgM]] and all [[IgG]] subclasses except [[Immunoglobulin_G#Subclasses|IgG4]] are able to initiate the complement system.
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