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ClueBot NG (talk | contribs) m Reverting possible vandalism by 66.27.46.3 to version by Boghog. Report False Positive? Thanks, ClueBot NG. (3307701) (Bot) |
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'''X-linked dominant inheritance''', sometimes referred to as '''X-linked dominance''', is a mode of [[genetics|genetic inheritance]] by which a [[dominant gene]] is carried on the [[X chromosome]]. As an inheritance pattern, it is less common than the [[X-linked recessive inheritance|X-linked recessive]] type. In medicine, X-linked dominant inheritance indicates that a gene responsible for a [[genetic disorder]] is located on the X chromosome, and only one copy of the [[allele]] is sufficient to cause the disorder when inherited from a parent who has the disorder. In this case, someone who [[Gene expression|expresses]] an X-linked dominant allele will exhibit the disorder and be considered affected.
X-linked dominant traits do not necessarily affect males more than females (unlike [[X-linked recessive]] traits). The exact pattern of inheritance varies, depending on whether the father or the mother has the trait of interest. All fathers that are affected by an X-linked dominant disorder
Some scholars have suggested discontinuing the terms dominant and recessive when referring to X-linked inheritance due to the multiple mechanisms that can result in the expression of X-linked traits in females, which include cell autonomous expression, [[skewed X-inactivation]], clonal expansion
==Genetics==
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