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* Virus Orthologous Clusters:<ref>{{cite web|url=http://athena.bioc.uvic.ca/tools/VOCS|title=VOCS - Viral Bioinformatics Resource Center|work=uvic.ca}}</ref> A viral protein sequence clustering database; contains all predicted genes from eleven virus families organized into ortholog groups by BLASTP similarity
* Skipredudant EMBOSS tool<ref>{{cite web|url=http://bioweb2.pasteur.fr/docs/EMBOSS/skipredundant.html|title=EMBOSS: skipredundant|work=pasteur.fr}}</ref> to remove redundant sequences from a set
* CLUSS<ref>http://prospectus.usherbrooke.ca/CLUSS/</ref> Algorithm<ref>{{cite web|url=https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-8-286|title=CLUSS Algorithm : Clustering non-alignable protein sequences|work=prospectus.usherbrooke.ca}}</ref> to identify groups of structurally, functionally, or evolutionarily related sequences.
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