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→Further reading: +general factor of psychoticness discussion of SNP heritability |
→Psychological: +Neuroticism/sex-link |
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* brain region activity response to faces<ref>[http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004523 "Global Genetic Variations Predict Brain Response to Faces"], Dickie et al 2014</ref><!-- too many, over too many conditions, to bother listing -->
* [[Big Five personality traits]]
** [[Neuroticism]] (autosomal): 0.06(0.03),<ref name="Vinkhuyzen2012">[http://www.nature.com/tp/journal/v2/n4/full/tp201227a.html "Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion"], Vinkhuyzen et al 2012</ref> 0.147(0.07)/0.157(0.16),<ref>[http://www.cs.princeton.edu/~bee/pubs/DeMoor-JAMA-2015.pdf "Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder"], De Moor et al 2015</ref> 0.15(0.08),<ref name="Power2015">[http://www.philosonic.com/michaelpluess_construction/Files/PowerPluess_2015_Heritability%20estimates%20of%20the%20Big%20Five%20personality%20traits%20based%20on%20common%20genetic%20variants.pdf "Heritability estimates of the Big Five personality traits based on common genetic variants"], Power & Pluess 2015</ref> 0.156(0.0074),<ref>[http://www.gwern.net/docs/genetics/2016-smith.pdf "Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci"], Smith et al 2016</ref> 0.15(0.02),<ref name="Pierson2014"/> 0.15(0.02),<ref name="Weiss2016">Weiss et al 2016, [https://www.cambridge.org/core/journals/twin-research-and-human-genetics/article/personality-polygenes-positive-affect-and-life-satisfaction/4DB2BE673BF122FB9A0AF2147EED80C0/core-reader "Personality Polygenes, Positive Affect, and Life Satisfaction"]</ref> 0.108 (0.02),<ref name="Hill2017"/> 0.146(0.007)<ref name="Hill2017b">Hill et al 2017, [http://biorxiv.org/content/early/2017/06/06/146787 "Genetic contribution to two factors of neuroticism is associated with affluence, better health, and longer life"]</ref>, 0.1437(0.0042)<ref name="Luciano2018">Luciano et al 2018, [https://www.biorxiv.org/content/early/2018/08/27/401166 "The influence of X chromosome variants on trait neuroticism"]</ref>
*** X-chromosome only: 0.0034(0.00007)<ref name="Luciano2018"/>
*** rare/family variants: 0.192 (0.025)<ref name="Hill2017"/>
*** Neuroticism worry-vulnerability facet: 0.097(0.007)<ref name="Hill2017b"/>
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