Primitive neuroectodermal tumor: Difference between revisions

Revision as of 17:50, 28 March 2019

Revision as of 17:52, 28 March 2019

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'''Primitive neuroectodermal tumor''' ('''PNET''') is a malignant (cancerous) [[neural crest]] tumor.<ref>{{DorlandsDict|eight/000112249|primitive neuroectodermal tumor}}</ref> It is a rare [[tumor]], usually occurring in children and young adults under 25 years of age. The overall 5 year survival rate is about 53%.<ref name=Smoll20111>{{Cite journal | last1 = Smoll | first1 = N. R. | title = Relative survival of childhood and adult medulloblastomas and primitive neuroectodermal tumors (PNETs) | doi = 10.1002/cncr.26387 | journal = Cancer | volume = 118 | issue = 5 | pages = 1313–1322 | year = 2012 | pmid = 21837678| pmc = }}</ref>

It gets its name because the majority of the cells in the tumor are derived from [[neuroectoderm]], but have not developed and differentiated in the way a normal [[neuron]] would, and so the cells appear "primitive".