Automated tissue image analysis: Difference between revisions

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|issn=0018-9294
|doi=10.1109/TBME.1985.325587
|pmid=4054933 |url=http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4122137
}}</ref> or improve the prediction rate of recurrence of some cancers.<ref name="Teverovskiy_2004">
{{cite journal
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|pages=49–58
|doi=10.1080/01926230490451734
|pmid=15503664
|url=http://tpx.sagepub.com/content/32/2_suppl/49
}}</ref> Systems for automatically analyzing tissue samples also reduce costs and save time.<ref name="O'Gorman_1985"/>
 
High-performance [[Charge-coupled device|CCD cameras]] are used for acquiring the digital images. Coupled with advanced [[fluorescence microscope|widefield microscope]]s and various [[algorithms]] for [[Deconvolution#Optics and other imaging|image restoration]], this approach can provide better results than [[confocal microscope|confocal techniques]] at comparable speeds and lower costs.<ref name="Phukpattaranont_2007">
{{cite journal
|journal=IFMBE Proceedings
|year=2007
|volume=15
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|doi=10.1007/978-3-540-68017-8_63
|title=An Automatic Cell Counting Method for a Microscopic Tissue Image from Breast Cancer
|author1=Pornchai Phukpattaranont |author2=Pleumjit Boonyaphiphat |urlseries=http://www.springerlink.com/content/v46774v3124w764r/IFMBE Proceedings
|series=IFMBE Proceedings
|isbn=978-3-540-68016-1}}</ref>
 
==Processes==
The [[United States of America|United States]] [[Food and Drug Administration]] classifies these systems as [[medical device]]s, under the general instrumentation category of [[automatic test equipment]].<ref>{{cite book|url=https://books.google.com/books?id=nEHLxh9wxZIC&pg=PA80&lpg=PA80&dq=%22FDA+automatic+test+equipment%22 |title=Testing Computer Systems for FDA/MHRA Compliance - David Stokes - Google Books |publisher=Books.google.com |date= 2003-11-25|accessdate=2012-07-12|isbn=9780849321634|last1=Stokes |first1=David }}</ref>
 
ATIS have seven basic processes (sample preparation, image acquisition, image analysis, results reporting, data storage, network communication, and self-system diagnostics) and realization of these functions highly accurate hardware and well-integrated, complex, and expensive software.<ref>{{cite journal|doi=10.1016/j.aca.2005.11.083 |pmid=17723364 |title=Analytica Chimica Acta - Advances in cancer tissue microarray technology: Towards improved understanding and diagnostics |date= | volume=564 |issue=1 |journal=Analytica Chimica Acta |pages=74–81|pmc=2583100|year=2006 |last1=Chen |first1=W. |last2=Foran |first2=D. J. }}</ref>
 
===Preparation===
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|volume=392
|issue=1–3
|pages=220–226.
|journal=Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
|date=February 1997
|doi=10.1016/S0168-9002(97)00297-0