Cardiac neural crest: Difference between revisions

Revision as of 16:15, 28 December 2019

Revision as of 16:16, 28 December 2019

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<noinclude>{{User:RMCD bot/subject notice|1=Cardiac neural crest|2=Talk:Cardiac neural crest cells#Requested move 28 December 2019 }}

</noinclude>[[Neural crest]] cells are a group of temporary, [[Cell potency#Multipotency|multipotent]] (can give rise to some other types of cells but not all) cells that are pinched off during the formation of the [[neural tube]] (precursor to the [[spinal cord]] and brain) and therefore are found at the dorsal (top) region of the neural tube during development.<ref name ="Kirby (1987)">Kirby M. [http://www.nature.com/pr/journal/v21/n3/pdf/pr198744a.pdf "Cardiac morphogenesis: recent research advances."] ''Pediatric Research.'' 1987 21(3) 219 - 224.</ref> They are derived from the [[ectoderm]] germ layer, but are sometimes called the fourth germ layer because they are so important and give rise to so many other types of cells.<ref name="Kirby (1987)"/><ref name="Gilbert (2010)">Gilbert S. F. [https://www.ncbi.nlm.nih.gov/books/NBK10065/ "Developmental biology."] Sinauer Associates, Massachusetts, 2010 p373 - 389.</ref> They migrate throughout the body and create a large number of differentiated cells such as [[neuron]]s, glial cells, pigment-containing cells in skin, skeletal tissue cells in the head, and many more.<ref name="Kirby (1987)"/><ref name="Gilbert (2010)"/>

Cardiac neural crest cells (CNCCs) are a type of neural crest cells that migrate to the circumpharyngeal ridge (an arc-shape ridge above the [[pharyngeal arch]]es) and then into the 3rd, 4th and 6th pharyngeal arches and the cardiac outflow tract (OFT).<ref name="Kirby (1987)"/><ref name="Gilbert (2010)"/><ref name="Kuratani (1992)">Kuratani S. C. and Kirby M. L. "Migration and distribution of circumpharyngeal crest cells in the chick embryo: formation of the circumpharyngeal ridge and E/C8+ crest cells in the vertebrate head region." Anat. Rec. October 1992 234(2) p263 - 268 {{PMID|1384396}} {{doi|10.1002/ar.1092340213}}</ref>