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|doi=10.1080/01926230490451734
|pmid=15503664
|doi-access=free}}</ref> Systems for automatically analyzing tissue samples also reduce costs and save time.<ref name="O'Gorman_1985"/>
High-performance [[Charge-coupled device|CCD cameras]] are used for acquiring the digital images. Coupled with advanced [[fluorescence microscope|widefield microscope]]s and various [[algorithms]] for [[Deconvolution#Optics and other imaging|image restoration]], this approach can provide better results than [[confocal microscope|confocal techniques]] at comparable speeds and lower costs.<ref name="Phukpattaranont_2007">
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