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==Empirical evidence that randomization makes a difference==
Empirically differences between randomized and non-randomized studies,<ref>{{cite journal| doi=10.1002/14651858.MR000034.pub2|vauthors=Anglemyer A, Horvath HT, Bero L | title=Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials| journal=Cochrane Database Syst Rev|date=April 2014| pmid=24782322| volume=4|issue=4 | pages=MR000034}}</ref> and between adequately and inadequately randomized trials have been difficult to detect.<ref>{{cite journal| doi=10.1002/14651858.MR000012.pub3| vauthors=Odgaard-Jensen J, Vist G, etal |title=Randomisation to protect against selection bias in healthcare trials.| journal=Cochrane Database Syst Rev| date=April 2011|pmid=21491415|pages=MR000012| issue=4| pmc=7150228}}</ref><ref>{{cite journal| doi=10.1186/1745-6215-15-480|vauthors=Howick J, Mebius A |title=In search of justification for the unpredictability paradox| journal=Trials| year=2014| volume=15| pmid=25490908| pages=480| pmc=4295227}}</ref>
==See also==
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