Tablet press: Difference between revisions

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[[Image:Tablet press animation.gif|thumb|300px|A [https://www.senieer.com/tablet-or-pill-press-machine/ tablet press] in operation|alt=]]

A '''tablet press''' is a mechanical device that compresses [[Powder (substance)|powder]] into [[Tablet (pharmacy)|tablets]] of uniform size and weight. A tablet press can be used to manufacture tablets of a wide variety of materials, including [[pharmaceuticals]], nutraceuticals [[Nutraceuticalnutraceuticals]], cleaning products, industrial pellets and [[cosmetics]]. To form a tablet, the granulated powder material must be metered into a cavity formed by two [[Punch (engineering)|punches]] and a [[Die (manufacturing)|die]], and then the punches must be pressed together with great force to fuse the material together.<ref>{{cite book |author1=Schwartz, Joseph |author2=Lieberman, Herbert A. |author3=Lachman, Leon |title=Pharmaceutical dosage forms--tablets |publisher=Dekker |___location=New York |year=1989 |pages= |isbn=0-8247-8044-2 |oclc= |doi=}}</ref>

A tablet is formed by the combined pressing action of two punches and a die. In the first step of a typical operation, the bottom punch is lowered in the die creating a cavity into which the granulated feedstock is fed. The exact depth of the lower punch can be precisely controlled to meter the amount of powder that fills the cavity. The excess is scraped from the top of the die, and the lower punch is drawn down and temporarily covered to prevent spillage. Then, the upper punch is brought down into contact with the powder as the cover is removed. The force of compression is delivered by high pressure compression rolls which fuse the granulated material together into a hard tablet. After compression, the lower punch is raised to eject the tablet.<ref>{{cite book |author1=Isadore Kanfer |author2=Shargel, Leon |author3=Kanfer, Izadore |title=Generic drug product development: solid oral dosage forms |publisher=Marcel Dekker |___location=New York, N.Y |year=2005 |pages= |isbn=0-8247-5460-3 |oclc= |doi= |url-access=registration |url=https://archive.org/details/genericdrugdevel143leon }}</ref>