Functional Lumen Imaging Probe: Difference between revisions

Revision as of 23:31, 26 December 2020

Revision as of 17:20, 30 December 2020

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FLIP may be used for several indications to evaluate esophageal symptoms, such as dysphagia, chest pain, or regurgitation, or to assess response to treatment. FLIP is used to evaluate for esophageal motility disorders, such as [[achalasia]], [[diffuse esophageal spasm]], etc.<ref name=Savarino>{{cite journal |last1=Savarino |first1=E |last2=di Pietro |first2=M |last3=Bredenoord |first3=AJ |last4=Carlson |first4=DA |last5=Clarke |first5=JO |last6=Khan |first6=A |last7=Vela |first7=MF |last8=Yadlapati |first8=R |last9=Pohl |first9=D |last10=Pandolfino |first10=JE |last11=Roman |first11=S |last12=Gyawali |first12=CP |title=Use of the Functional Lumen Imaging Probe in Clinical Esophagology. |journal=The American journal of gastroenterology |date=November 2020 |volume=115 |issue=11 |pages=1786-1796 |doi=10.14309/ajg.0000000000000773 |pmid=33156096}}</ref> FLIP may be used as a complementary or alternative to esophageal manometry for evaluating esophageal outflow obstructive disorders, including achalasia. FLIP may be used as a complementary test for barium esophagram for evaluating esophageal outflow obstructive disorders. FLIP may be used to assess the effect of treatment for achalasia.

FLIP measurements may be used to guide intraoperative reflux surgery, or to assess the degree of fibrostenotic disease from eosinophilic esophagitis.<ref name=Savarino /><ref name=Hirano>{{cite journal |last1=Hirano |first1=I |last2=Pandolfino |first2=JE |last3=Boeckxstaens |first3=GE |title=Functional Lumen Imaging Probe for the Management of Esophageal Disorders: Expert Review From the Clinical Practice Updates Committee of the AGA Institute. |journal=Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association |date=March 2017 |volume=15 |issue=3 |pages=325-334 |doi=10.1016/j.cgh.2016.10.022 |pmid=28212976|pmc=5757507 }}</ref> FLIP may be used to guide endoscopic dilation of esophageal strictures.<ref name=Savarino />

While recommendations exist for its use, the evidence supporting the use of FLIP is of very low quality and further research would be useful in more clearly defining its role.<ref>{{cite journal |last1=Massey |first1=BT |title=Clinical Functional Lumen Imaging Probe Testing in Esophageal Disorders: A Need for Better Quality Evidence. |journal=The American journal of gastroenterology |date=November 2020 |volume=115 |issue=11 |pages=1799-1801 |doi=10.14309/ajg.0000000000000974 |pmid=33156098}}</ref><ref>{{cite journal |last1=Massey |first1=BT |title=Flip Technology for Assessing Esophageal Structural and Motor Disorders: a Skeptic's View. |journal=Current gastroenterology reports |date=10 July 2020 |volume=22 |issue=9 |pages=44 |doi=10.1007/s11894-020-00782-2 |pmid=32651682}}</ref>

==History==

Early development of impedence planimetry for evaluating the gastrointestinal tract began in the 1980s.<ref name=Gregersen>{{cite journal |last1=Gregersen |first1=H |last2=Lo |first2=KM |title=What Is the Future of Impedance Planimetry in Gastroenterology? |journal=Journal of neurogastroenterology and motility |date=30 April 2018 |volume=24 |issue=2 |pages=166-181 |doi=10.5056/jnm18013 |pmid=29605974|doi-access=free }}</ref> FLIP was first developed with a short balloon catheter, which measures distension across the esophagogastric junction.<ref name=DeVault /> A second generation device was later released, which measures secondary peristalsis proximal to the EGJ.<ref name=DeVault>{{cite journal |last1=DeVault |first1=KR |title=Functional luminal imaging probe: an evolving technology for the diagnosis of esophageal motility disorders. |journal=Gastrointestinal endoscopy |date=December 2019 |volume=90 |issue=6 |pages=924-925 |doi=10.1016/j.gie.2019.08.025 |pmid=31759418|doi-access=free }}</ref>

==See also==