Endothelin converting enzyme 1: Difference between revisions

Revision as of 00:42, 14 December 2020

Revision as of 20:17, 1 January 2021

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{{Infobox_gene}}

'''<span lang="fr" dir="ltr">Endothelin</span> converting enzyme 1''', also known as '''ECE1''', is an [[enzyme]] which in humans is encoded by the ''ECE1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ECE1 endothelin converting enzyme 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1889}}</ref><ref name="pmid7805846">{{cite journal | vauthors = Schmidt M, Kröger B, Jacob E, Seulberger H, Subkowski T, Otter R, Meyer T, Schmalzing G, Hillen H | title = Molecular characterization of human and bovine endothelin converting enzyme (ECE-1) | journal = FEBS Lett. | volume = 356 | issue = 2–3 | pages = 238–43 |date=December 1994 | pmid = 7805846 | doi = 10.1016/0014-5793(94)01277-6| doi-access = free }}</ref><ref name="pmid7864876">{{cite journal | vauthors = Shimada K, Matsushita Y, Wakabayashi K, Takahashi M, Matsubara A, Iijima Y, Tanzawa K | title = Cloning and functional expression of human endothelin-converting enzyme cDNA | journal = Biochem. Biophys. Res. Commun. | volume = 207 | issue = 2 | pages = 807–12 |date=February 1995 | pmid = 7864876 | doi = 10.1006/bbrc.1995.1258 }}</ref>

== Function ==

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{{refbegin | 2}}

*{{cite journal | vauthors=Yorimitsu K, Moroi K, Inagaki N |title=Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2 |journal=Biochem. Biophys. Res. Commun. |volume=208 |issue= 2 |pages= 721–7 |year= 1995 |pmid= 7695628 |doi=10.1006/bbrc.1995.1397 |display-authors=etal}}

*{{cite journal | vauthors=Schmidt M, Kröger B, Jacob E |title=Molecular characterization of human and bovine endothelin converting enzyme (ECE-1) |journal=FEBS Lett. |volume=356 |issue= 2–3 |pages= 238–43 |year= 1995 |pmid= 7805846 |doi=10.1016/0014-5793(94)01277-6 |display-authors=etal|doi-access=free }}

*{{cite journal | vauthors=Shimada K, Matsushita Y, Wakabayashi K |title=Cloning and functional expression of human endothelin-converting enzyme cDNA |journal=Biochem. Biophys. Res. Commun. |volume=207 |issue= 2 |pages= 807–12 |year= 1995 |pmid= 7864876 |doi= 10.1006/bbrc.1995.1258 |display-authors=etal}}

*{{cite journal | vauthors=Valdenaire O, Rohrbacher E, Mattei MG |title=Organization of the gene encoding the human endothelin-converting enzyme (ECE-1) |journal=J. Biol. Chem. |volume=270 |issue= 50 |pages= 29794–8 |year= 1996 |pmid= 8530372 |doi=10.1074/jbc.270.50.29794 |doi-access=free }}

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*{{cite journal | vauthors=Hofstra RM, Valdenaire O, Arch E |title=A loss-of-function mutation in the endothelin-converting enzyme 1 (ECE-1) associated with Hirschsprung disease, cardiac defects, and autonomic dysfunction |journal=Am. J. Hum. Genet. |volume=64 |issue= 1 |pages= 304–8 |year= 1999 |pmid= 9915973 |doi=10.1086/302184 | pmc=1377732 |display-authors=etal}}

*{{cite journal | vauthors=Lee S, Lin M, Mele A |title=Proteolytic processing of big endothelin-3 by the kell blood group protein |journal=Blood |volume=94 |issue= 4 |pages= 1440–50 |year= 1999 |pmid= 10438732 |doi= 10.1182/blood.V94.4.1440|display-authors=etal}}

*{{cite journal | vauthors=Valdenaire O, Lepailleur-Enouf D, Egidy G |title=A fourth isoform of endothelin-converting enzyme (ECE-1) is generated from an additional promoter molecular cloning and characterization |journal=Eur. J. Biochem. |volume=264 |issue= 2 |pages= 341–9 |year= 1999 |pmid= 10491078 |doi=10.1046/j.1432-1327.1999.00602.x |display-authors=etal|doi-access=free }}

*{{cite journal | vauthors=Fahnoe DC, Johnson GD, Herman SB, Ahn K |title=Disulfide bonds in big ET-1 are essential for the specific cleavage at the Trp(21)-Val(22) bond by soluble endothelin converting enzyme-1 from baculovirus/insect cells |journal=Arch. Biochem. Biophys. |volume=373 |issue= 2 |pages= 385–93 |year= 2000 |pmid= 10620363 |doi= 10.1006/abbi.1999.1586 }}

*{{cite journal | vauthors=López-Ongil S, Senchak V, Saura M |title=Superoxide regulation of endothelin-converting enzyme |journal=J. Biol. Chem. |volume=275 |issue= 34 |pages= 26423–7 |year= 2000 |pmid= 10833511 |doi= 10.1074/jbc.M000767200 |display-authors=etal|doi-access=free }}