These are the Billboard magazine Modern Rock Tracks number one hits of 2005.
| Issue Date | Song | Artist |
| January 1 | Boulevard of Broken Dreams | Green Day |
| January 8 | Boulevard of Broken Dreams | Green Day |
| January 15 | Boulevard of Broken Dreams | Green Day |
| January 22 | Boulevard of Broken Dreams | Green Day |
| January 29 | Boulevard of Broken Dreams | Green Day |
| February 5 | Boulevard of Broken Dreams | Green Day |
| February 12 | Boulevard of Broken Dreams | Green Day |
| February 19 | Boulevard of Broken Dreams | Green Day |
| February 26 | Boulevard of Broken Dreams | Green Day |
| March 5 | Boulevard of Broken Dreams | Green Day |
| March 12 | Boulevard of Broken Dreams | Green Day |
| March 19 | Boulevard of Broken Dreams | Green Day |
| march 26 | Boulevard of Broken Dreams | Green Day |
| April 2 | E-Pro | Beck |
| April 9 | Be Yourself | Audioslave |
| April 16 | Be Yourself | Audioslave |
| April 23 | Be Yourself | Audioslave |
| April 30 | Be Yourself | Audioslave |
| May 7 | Holiday | Green Day |
| May 14 | Holiday | Green Day |
| May 21 | Holiday | Green Day |
| May 28 | The Hand That Feeds | Nine Inch Nails |
| June 4 | The Hand That Feeds | Nine Inch Nails |
| June 11 | The Hand That Feeds | Nine Inch Nails |
| June 18 | The Hand That Feeds | Nine Inch Nails |
| June 25 | The Hand That Feeds | Nine Inch Nails |
| July 2 | Beverly Hills | Weezer |
| July 9 | Best of You | Foo Fighters |
| July 16 | Best of You | Foo Fighters |
| July 23 | Best of You | Foo Fighters |
| July 30 | Best of You | Foo Fighters |
| August 6 | Best of You | Foo Fighters |
| August 13 | Best of You | Foo Fighters |
| August 20 | Best of You | Foo Fighters |
| August 27 | Feel Good Inc. | Gorillaz |
| September 3 | Feel Good Inc. | Gorillaz |
| September 10 | Feel Good Inc. | Gorillaz |
| September 17 | Feel Good Inc. | Gorillaz |
| September 24 | Feel Good Inc. | Gorillaz |
| October 1 | Feel Good Inc. | Gorillaz |
| October 8 | Feel Good Inc. | Gorillaz |
| October 15 | Feel Good Inc. | Gorillaz |
| October 22 | Only | Nine Inch Nails |
| October 29 | Only | Nine Inch Nails |
| November 5 | Only | Nine Inch Nails |
| November 12 | Only | Nine Inch Nails |
| November 19 | Only | Nine Inch Nails |
| November 26 | DOA | Foo Fighters |
| December 3 | DOA | Foo Fighters |
| December 10 | Only | Nine Inch Nails |
| December 17 | Only | Nine Inch Nails |
| December 24 | DOA | Foo Fighters |
| December 31 | DOA | Foo Fighters |