Lander–Green algorithm

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The Lander–Green algorithm is an algorithm, due to Eric Lander and Philip Green for computing the likelihood of observed genotype data given a pedigree. It is appropriate for relatively small pedigrees and a large number of markers. It is used in the analysis of genetic linkage.[1] [2]

References

  1. ^ Lander and Green (1987) PNAS 84:2363-7
  2. ^ Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers [1]