Wikipedia

CYP2C8

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Cytochrome P450 2C8 (abbreviated CYP2C8), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.

cytochrome P450, family 2, subfamily C, polypeptide 8
Identifiers
SymbolCYP2C8
NCBI gene1558
HGNC2622
OMIM601129
RefSeqNM_000770
UniProtP10632
Other data
LocusChr. 10 q24.1
Search for
StructuresSwiss-model
DomainsInterPro

CYP2C8 Ligands

Selected inducers, inhibitors and substrates of CYP2C81
Type Agent
inducers rifampicin
inhibitors gemfibrozil, glitazones (rosiglitazone, pioglitazone, etc), montelukast, quercetin, trimethoprim
substrates cerivastatin, paclitaxel, repaglinide, torasemide
Notes:
  1. Where classes of agents are listed, there may be exceptions within the class.

See also

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