Cetirizine hydrochloride (marketed as Zyrtec®, or Zirtek® in the United Kingdom, as Reactine® in Canada, and as Virlix® in Italy) is a medication used for the treatment of allergies, hay fever, angioedema, and hives. It is a second-generation H1-receptor antagonist antihistamine and works by blocking H1 histamine receptors. It is a major metabolite of hydroxyzine, and has the same basic side effects.
- It has long duration of action
- No reported cardia toxicity associated with the use of this drug
- Minimal penetration of the Blood_brain_barrier
- However it is associated with high sedating effects compared with the other non-sedating antihistamines
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