This is a list of famous Native Americans (Indigenous peoples of the Americas).
In Canada
- Gary Farmer, actor and filmmaker
- Graham Greene, actor
- Tomson Highway, playwright, novelist, and children's author.
- Louis Riel, politician
- Buffy Sainte-Marie, musician
- Matthew Coon Come, Grand Chief of the Assembly of First Nations
- Stephen Kakfwi, premier of the Northwest Territories
- Paul Okalik, premier of Nunavut
- Bl. Kateri Tekakwitha, first Native American considered for Sainthood by the Roman Catholic Church
In Guatemala
- Miguel Angel Asturias, novelist, Nobel prize winner in literature
- Rigoberta Menchú Tum, activist
In the Caribbean
- Agueybana - "supreme cacique" in Puerto Rico
- Hatuey (Taíno)
In Mexico
- Benito Juárez, President
- Frida Kahlo, painter (mother Mestizo, father Jewish)
- La Malinche, Translator
- Moctezuma II (Aztec) ruler
- Commandante Ramona, EZLN leader
- Emilio Hernandez, film director, actor
- Porfirio Diaz, President
In the United States
- Tori Amos, musician (part Cherokee)
- Jessica Biel, actress (part Choctaw)
- Big Foot
- Black Elk
- Black Hawk
- Jimmy Carl Black (Cheyenne), musician
- Blue Jacket (Shawnee)
- Billy Bowlegs (Seminole)
- Buckongahelas (Lenape)
- Ben Nighthorse Campbell (Cheyenne), senator
- Captain Jack (Modoc)
- Brad Carson, U.S. Representative
- Cher
- Cochise
- Tom Cole, U.S. Representative, Chickasaw
- Cornplanter (Seneca)
- Cornstalk (Shawnee)
- Crazy Horse
- Charles Curtis (Kaw), U.S. Vice-President
- Chad 'Corntassel' Smith, Principal Chief of Cherokee Nation of Oklahoma
- Jesse Ed Davis, guitarist (full-blooded Kiowa tribe)
- Deganawida
- Johnny Depp
- Cameron Diaz
- Michael Dorris, author
- Louise Erdrich, author
- Geronimo
- Ira Hayes (Pima), World War II national hero
- Hayowentha
- William Least Heat-Moon, author
- Ishi
- Angelina Jolie, actress (mother part-Haudenosaunee)
- Chief Joseph (Nez Perce)
- Winona LaDuke, political activist (Chippewa father)
- Chief Logan (Mingo)
- Russell Means (Sioux), actor, political activist, writer
- Wilma Mankiller
- Alexander McGillivray (Muscogee (Creek))
- Billy Mills, Olympic gold medalist at 10,000 meters in 1964
- Demi Moore, actress
- Tiger Woods, golfer
- Nampeyo, Hopi potter
- Neolin, The "Delaware Prophet" (Lenape)
- Wayne Newton, singer
- Chuck Norris, actor
- Osceola
- Eli Parker
- Quanah Parker
- Leonard Peltier
- King Philip (Metacom)
- Pocahontas
- Pontiac (Ottawa)
- The Prophet (Tenskwatawa) (Shawnee)
- Rain in the Face
- Lozen
- Red Cloud
- Red Jacket
- Rita Coolidge
- Nikki Reed, actress (mother part-Cherokee)
- Major Ridge (Cherokee)
- Robbie Robertson
- Will Rogers
- Sacagawea
- Kelvin Sampson, head basketball coach at University of Oklahoma
- Chief Seattle
- Sakayengwaraton
- Sequoyah (Cherokee)
- Shingas (Lenape)
- Leslie Marmon Silko
- Sitting Bull (Sioux)
- Squanto
- Maria Tallchief
- Gladys Tantaquidgeon
- Tecumseh (Shawnee)
- Bl. Kateri Tekakwitha, first Native American considered for sainthood by the Roman Catholic Church
- Jim Thorpe (Sac and Fox, native name Wa-Tho-Huk)
- Gerald Vizenor, writer and academic
- Stand Watie
- James Welch
- White Eyes (Lenape)
- Wovoka
- Ray Young Bear
- Zitkala-Ša
- Joseph Brant Later years in Canada
- Yvonne Kauger-Oklahoma Supreme Court Justice