Mitochondrial translational release factor 1

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Mitochondrial translational release factor 1, also known as MTRF1 is a human gene.[1][2]

mitochondrial translational release factor 1
Identifiers
SymbolMTRF1
NCBI gene9617
HGNC7469
OMIM604601
RefSeqNM_004294
UniProtO75570
Other data
LocusChr. 13 q14.1-14.3
Search for
StructuresSwiss-model
DomainsInterPro

The protein encoded by this gene directs the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis.

References

  1. ^ Zhang Y, Spremulli LL (1998). "Identification and cloning of human mitochondrial translational release factor 1 and the ribosome recycling factor". Biochimica et biophysica acta. 1443 (1–2): 245–50. doi:10.1016/S0167-4781(98)00223-1. PMID 9838146. {{cite journal}}: Unknown parameter |month= ignored (help)
  2. ^ Hansen LL, Jørgensen R, Justesen J (2000). "Assignment of the human mitochondrial translational release factor 1 (MTRF1) to chromosome 13q14.1-->q14.3 and of the human mitochondrial ribosome recycling factor (MRRF) to chromosome 9q32-->q34.1 with radiation hybrid mapping". Cytogenetics and cell genetics. 88 (1–2): 91–2. doi:10.1159/000015494. PMID 10773675.{{cite journal}}: CS1 maint: multiple names: authors list (link)