The epigenetic code is hypothesised to be a defining code in every eukaryotic cell consisting of the specific epigenetic modification in each cell. It consists of histone modifications defined by the histone code and additional epigenetic modifications such as DNA methylation. The base for the epigenetic code is a system above the genetic code of a single cell. While in one individual the genetic code in each cell is the same, the epigenetic code is tissue and cell specific [1]. Unlike genetics, the epigenetic code can be multidimensional in nature. It could include any of the three major cellular macromolecucles; namely, DNA, RNA, and protein. In some ciliates potential structural codes have also been suggested tends to be multidimensional in nature [2].
See also
References
- ^ cite journal |author=Turner B |title=Defining an epigenetic code |journal=Nat Cell Biol |volume=9 |issue=1 |pages=2–6 |year=2007 |pmid=17199124 |doi=10.1038/ncb0107-2
- ^ Chahwan R., Wontakal S.N., and Roa S. (2011). "The multidimensional nature of epigenetic information and its role in disease." Discovery Medicine, Mar;11(58):233-43. PMID: 21447282 [1].
- Turner B (2007). "Defining an epigenetic code". Nat Cell Biol. 9 (1): 2–6. doi:10.1038/ncb0107-2. PMID 17199124.