The cardiac neural crest complex is a form of neural crest.[1]
| Cardiac neural crest complex | |
|---|---|
| Details | |
| Identifiers | |
| Latin | complexus cristae neuralis cardiacus |
| TE | neural crest complex_by_E4.0.3.5.0.3.1 E4.0.3.5.0.3.1 |
| Anatomical terminology | |
The cardiac neural crest develops from the dorsal neural tube.[2] It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart.
- Other Migration Locations:
- Into the pharyngeal arches and Truncus arteriosus (embryology), forming the aorticopulmonary septum[3] and the smooth muscle of great arteries.
- Anterior of the aorta to become the four pre-aortic ganglia (celiac ganglion, superior mesenteric ganglion, inferior mesenteric ganglion and aortical renal ganglia)
References
- ^ "The Neural Crest". Retrieved 2009-05-31.
- ^ Sun X, Zhang R, Lin X, Xu X (2008). "Wnt3a regulates the development of cardiac neural crest cells by modulating expression of cysteine-rich intestinal protein 2 in rhombomere 6". Circ. Res. 102 (7): 831–9. doi:10.1161/CIRCRESAHA.107.166488. PMID 18292601.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM (2000). "Fate of the mammalian cardiac neural crest". Development. 127 (8): 1607–16. PMID 10725237.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Varadkar P, Kraman M, Despres D, Ma G, Lozier J, McCright B (2008). "Notch2 is required for the proliferation of cardiac neural crest-derived smooth muscle cells". Dev. Dyn. 237 (4): 1144–52. doi:10.1002/dvdy.21502. PMID 18330927.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link)
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The FGF8 that is present in the endoderm is regulated by cardiac neural crest-derived cells (Hutson et al., 2006) he cardiac neural crest, in addition to forming the outflow tract septum, also has an indirect effect on the secondary heart field and thus outflow myocardium development, and that the FGF8 pathway is a common thread between the two populations.