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Simple Modular Architecture Research Tool

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Simple Modular Architecture Research Tool (SMART) is a biological database that used in the identification and analysis of protein domains within protein sequences.[1][2] SMART uses profile-hidden Markov models built from multiple sequence alignments to detect protein domains in protein sequences. The most recent release of SMART contains 1,009 ___domain models.[3] Data from SMART was used in creating the Conserved Domain Database collection and is also distributed as part of the InterPro database.[4] The database is hosted by the European Molecular Biology Laboratory in Heidelberg.

SMART
Content
DescriptionIdentification scheme for protein domains.
Data types
captured		Protein domains
Organismsall
Contact
Research centerEuropean Molecular Biology Laboratory
Primary citationPMID 18978020
Access
Websitehttp://smart.embl-heidelberg.de
Miscellaneous
LicenseFree to academics, but not commercial users
Version7
Curation policyYes

References

  1. ^ Schultz J, Milpetz F, Bork P, Ponting CP (May 1998). "SMART, a simple modular architecture research tool: identification of signaling domains". Proc. Natl. Acad. Sci. U.S.A. 95 (11): 5857–64. doi:10.1073/pnas.95.11.5857. PMC 34487. PMID 9600884.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Letunic I, Doerks T, Bork P (January 2009). "SMART 6: recent updates and new developments". Nucleic Acids Res. 37 (Database issue): D229–32. doi:10.1093/nar/gkn808. PMC 2686533. PMID 18978020.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Letunic I, Doerks T, Bork P (January 2012). "SMART 7: recent updates to the protein ___domain annotation resource". Nucleic Acids Res. 40 (Database issue): D302–5. doi:10.1093/nar/gkr931. PMC 3245027. PMID 22053084.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ Mulder NJ, Apweiler R, Attwood TK; et al. (September 2002). "InterPro: an integrated documentation resource for protein families, domains and functional sites". Brief. Bioinformatics. 3 (3): 225–35. PMID 12230031. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)


   

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