Gene set enrichment analysis

Gene set enrichment or functional enrichment analysis is a method to identify classes of genes or proteins that are over-represented in a large set of genes or proteins. The method uses statistical approaches to identify significantly enriched or depleted groups of genes. Microarray and proteomics results often identify thousands of genes which are used for the analysis.^[1]

References

^ Subramanian A, Tamayo P, Mootha VK; et al. (2005). "Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles". Proc. Natl. Acad. Sci. U.S.A. 102 (43): 15545–50. doi:10.1073/pnas.0506580102. PMC 1239896. PMID 16199517. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)

[1] Subramanian A, Tamayo P, Mootha VK; et al. (2005). "Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles". Proc. Natl. Acad. Sci. U.S.A. 102 (43): 15545–50. doi:10.1073/pnas.0506580102. PMC 1239896. PMID 16199517. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)

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