All-trans-nonaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) (EC 2.5.1.85, nonaprenyl diphosphate synthase, solanesyl diphosphate synthase, At-SPS2, At-SPS1, SPS1, SPS2) is an enzyme with systematic name geranylgeranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 5 isopentenyl units).[1][2][3] This enzyme catalyses the following chemical reaction
| All-trans-nonaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.85 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- geranylgeranyl diphosphate + 5 isopentenyl diphosphate 5 diphosphate + all-trans-nonaprenyl diphosphate
Geranylgeranyl diphosphate is preferred over farnesyl diphosphate as allylic substrate.
References
- ^ Hirooka, K., Bamba, T., Fukusaki, E. and Kobayashi, A. (2003). "Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase". Biochem. J. 370 (Pt 2): 679–686. doi:10.1042/BJ20021311. PMC 1223189. PMID 12437513.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Hirooka, K., Izumi, Y., An, C.I., Nakazawa, Y., Fukusaki, E. and Kobayashi, A. (2005). "Functional analysis of two solanesyl diphosphate synthases from Arabidopsis thaliana". Biosci. Biotechnol. Biochem. 69 (3): 592–601. doi:10.1271/bbb.69.592. PMID 15784989.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Jun, L., Saiki, R., Tatsumi, K., Nakagawa, T. and Kawamukai, M. (2004). "Identification and subcellular localization of two solanesyl diphosphate synthases from Arabidopsis thaliana". Plant Cell Physiol. 45 (12): 1882–1888. doi:10.1093/pcp/pch211. PMID 15653808.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- All-trans-nonaprenyl+diphosphate+synthase+(geranylgeranyl-diphosphate+specific) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)