Mike may refer to:
- The shortened version of the boys name Michael
In technology:
- Ivy Mike, the first hydrogen bomb
- Mike, short for Microphone, an acoustic to electric transducer that converts sound into an electrical signal
- Mike (cellular network), an iDEN cellular phone network in Canada
In fiction:
- Mike, a character from The Railway Series books by Rev. W. Awdry
- Mike (novel), a novel by P. G. Wodehouse
- Mike (Cro character), fictional character from Cro
In music:
- Mike, a song by Xiu Xiu from the album Fabulous Muscles
- Mike (album), the self titled album released by the winner of Indonesian Idol 2
In other fields:
- Mike, M in the NATO phonetic alphabet
- Mike, middle linebacker in American football
- Mike the Headless Chicken, a Wyandotte rooster that lived for 18 months after his head had been cut off
- Mike Goldman, Australian comedian known for his voiceover work and presenting of Big Brother Australia shows