William Cook can refer to:
- William Cook (entrepreneur), the founder of the Cook Group, a medical equipment manufacturer.
- William Cook (street vendor), the brother of Mumia Abu-Jamal, convicted for the murder of police officer Daniel Faulkner
- William Edwards Cook, American-born expatriate artist, architectural patron, and long-time friend of writer Gertrude Stein.
This disambiguation page lists articles associated with the title William Cook.
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