3C-E

3C-E (3,5-Dimethoxy-4-ethoxyamphetamine) is a psychedelic of the amphetamine class. It was first synthesized by Alexander Shulgin. In his book PiHKAL, Shulgin lists the dosage range as 30 to 60 mg, consumed orally.^[1][2] The duration of action was stated to be 8–12 hours.^[1]

3C-E

Legal status
Legal status	CA: Schedule I DE: NpSG (Industrial and scientific use only) UK: Class B US: Analogue of a Schedule I drug, possibly illegal under the Federal Analog Act
Identifiers
IUPAC name 1-(4-Ethoxy-3,5-dimethoxyphenyl)propan-2-amine
CAS Number	146849-92-5 Y
PubChem CID	44350137
ChemSpider	21106237
UNII	W9QX56V5RU
ChEMBL	ChEMBL128038
CompTox Dashboard (EPA)	DTXSID40658382
Chemical and physical data
Formula	C13H21NO3
Molar mass	239.315 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOc1c(cc(cc1OC)CC(C)N)OC
InChI InChI=1S/C13H21NO3/c1-5-17-13-11(15-3)7-10(6-9(2)14)8-12(13)16-4/h7-9H,5-6,14H2,1-4H3 Key:AHLXCGRWNKUNTQ-UHFFFAOYSA-N

This compound is the amphetamine analog of escaline.

See also

• 3C (psychedelics)
• 3C-P
• 2,5-Dimethoxy-4-ethoxyamphetamine (MEM)
• Proscaline
• Mescaline

References

1. PiHKAL entry
2. Halberstadt AL, Chatha M, Klein AK, Wallach J, Brandt SD (May 2020). "Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species" (PDF). Neuropharmacology. 167: 107933. doi:10.1016/j.neuropharm.2019.107933. PMC 9191653. PMID 31917152. Table 4 Human potency data for selected hallucinogens. [...]