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Federal
Host gene expression is associated with viral shedding magnitude in blue-winged teals (Spatula discors) infected with low-path avian influenza virus
U.S. Environmental Protection Agency —
Intraspecific variation in host infectiousness affects disease transmission dynamics in human, domestic animal, and many wildlife host-pathogen systems including... -
Federal
HepRG exposed to microcystin LR and RR gene expression
U.S. Environmental Protection Agency —
RNA-seq data from HepaRG cells exposed for 2 hours to microcystin-LR and -RR at multiple concentrations each. This dataset is associated with the following... -
Federal
TempO-seq and RNA-seq gene expression levels are highly correlated for most genes: A comparison using 39 human cell lines
U.S. Environmental Protection Agency —
Journal article published in PLOS One, Vol 20, Issue 5, e0320862, 2025; DOI: https://doi.org/10.1371/journal.pone.0320862; PMC12064016. The datasets generated and... -
Federal
ESR1 expression and DNA methylation data for FHM exposed to EE2
U.S. Environmental Protection Agency —
This dataset contains data for adult male fathead minnows exposed to EE2 (a synthetic estrogen). It is a targeted study on the response of the esr1 gene (expression... -
Federal
Multigene biomarkers of pyrethroid exposure: exploratory experiments
U.S. Environmental Protection Agency —
Gene expression microarray measurements in Pimephales promelas before and after pyrethroid exposure. This dataset is associated with the following publication:... -
Federal
Adult FHM liver gene expression - treated with EE2
U.S. Environmental Protection Agency —
Male adult FHM liver treated with EE2 - gene expresssion - Agilent-036574 FHM_8x60K_V2 array design. This dataset is associated with the following publication:... -
Federal
Effects of Age and Exposure Duration on the Sensitivity of Early Life Stage Fathead Minnow (Pimephales promelas) to Waterborne Propranolol Exposure
U.S. Environmental Protection Agency —
Given that larval fish stages provide opportunities for development of stressor-selective screening level tests, this work aimed to investigate the optimal age of... -
Federal
A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics
U.S. Environmental Protection Agency —
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in... -
Federal
Intratracheal instillation of respirable particulate matter elicits neuroendocrine activation
U.S. Environmental Protection Agency —
Objective: Inhalation of ozone activates central sympathetic-adrenal-medullary and hypothalamic-pituitary-adrenal stress axes. While airway neural networks are known... -
Federal
Screening an alternative flame retardant using biological and transcriptomic endpoints in fish embryos
U.S. Environmental Protection Agency —
GEO accession information for omics RNA-seq data. This dataset is not publicly accessible because: EPA cannot release personally identifiable information regarding... -
Federal
Acute Ozone-Induced Transcriptional Changes in Markers of Oxidative Stress and Glucocorticoid Signaling in the Rat Hippocampus and Hypothalamus are Sex-Specific
U.S. Environmental Protection Agency —
The dataset is comprised of multiple data-frames. Our focus is on sex and brain region specific responses to ozone in a rat model. The PCR data describes the gene...