117 datasets found
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Federal
Host gene expression is associated with viral shedding magnitude in blue-winged teals (Spatula discors) infected with low-path avian influenza virus
U.S. Environmental Protection Agency —
Intraspecific variation in host infectiousness affects disease transmission dynamics in human, domestic animal, and many wildlife host-pathogen systems including... -
Federal
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol
U.S. Department of Health & Human Services —
Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket.... -
Federal
Model-based cluster analysis of microarray gene-expression data
U.S. Department of Health & Human Services —
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data.... -
Federal
Analysis of a human brain transcriptome map
U.S. Department of Health & Human Services —
Background Genome wide transcriptome maps can provide tools to identify candidate genes that are over-expressed or silenced in certain disease tissue and increase our... -
Federal
Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer
U.S. Department of Health & Human Services —
Background We have used commercially available cDNA arrays to identify EphB4 as a gene that is up-regulated in colon cancer tissue when compared with matched normal... -
Federal
Little qualitative RNA misexpression in sterile male F
U.S. Department of Health & Human Services —
Background Although the genetics of hybrid sterility has been the subject of evolutionary studies for over sixty years, no one has shown the reason(s) why alleles... -
Federal
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
U.S. Department of Health & Human Services —
Using real-time reverse transcription PCR ten housekeeping genes from different abundance and functional classes in various human tissues were evaluated. The... -
Federal
Hepatic gene expression transcript counts in liver samples of American kestrels
Department of the Interior —
A number of brominated flame retardants (BFRs) have been reported to interfere with the thyroid signaling pathway and cause oxidative stress in birds, yet the... -
Federal
Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts
U.S. Department of Health & Human Services —
Background Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional... -
Federal
Vector algebra in the analysis of genome-wide expression data
U.S. Department of Health & Human Services —
Background Data from thousands of transcription-profiling experiments in organisms ranging from yeast to humans are now publicly available. How best to analyze these... -
Federal
Permutation-validated principal components analysis of microarray data
U.S. Department of Health & Human Services —
Background In microarray data analysis, the comparison of gene-expression profiles with respect to different conditions and the selection of biologically interesting... -
Federal
Survey of transcripts in the adult
U.S. Department of Health & Human Services —
Background: Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then... -
Federal
Analysis of strain and regional variation in gene expression in mouse brain
U.S. Department of Health & Human Services —
Background We performed a statistical analysis of a previously published set of gene expression microarray data from six different brain regions in two mouse strains.... -
Federal
Evaluation of differential gene expression during behavioral development in the honeybee using microarrays and northern blots
U.S. Department of Health & Human Services —
Background The honeybee (Apis mellifera) has been used with great success in a variety of behavioral studies. The lack of genomic tools in this species has, however,... -
Federal
Normalization and analysis of DNA microarray data by self-consistency and local regression
U.S. Department of Health & Human Services —
A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression... -
Federal
Plant Expression Database
Department of Agriculture —
[NOTE: PLEXdb is no longer available online. Oct 2019.] PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens.... -
Federal
HepRG exposed to microcystin LR and RR gene expression
U.S. Environmental Protection Agency —
RNA-seq data from HepaRG cells exposed for 2 hours to microcystin-LR and -RR at multiple concentrations each. This dataset is associated with the following... -
Federal
Empirical characterization of the expression ratio noise structure in high-density oligonucleotide arrays
U.S. Department of Health & Human Services —
Background High-density oligonucleotide arrays (HDONAs) are a powerful tool for assessing differential mRNA expression levels. To establish the statistical... -
Federal
Data from: Genomic structural differences between cattle and River Buffalo identified through comparative genomic and transcriptomic analysis
Department of Agriculture —
Water buffalo (Bubalus bubalis L.) is an important livestock species worldwide. Like many other livestock species, water buffalo lacks high quality and continuous... -
Federal
Expression profiles during honeybee caste determination
U.S. Department of Health & Human Services —
Background Depending on their larval environment, female honeybees develop into either queens or workers. As in other polyphenisms, this developmental switch depends...
117 datasets found