63 datasets found
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Federal
Characterization of Epigenetic Regulation in an Extraterrestrial Environment: The Arabidopsis Spaceflight Methylome [Bisulfite-seq]
National Aeronautics and Space Administration —
When germinated and grown on-board the ISS (International Space Station) plant do not exhibit abnormal structures but they do have altered growth habits and this... -
Federal
Effects of 21 days of bedrest on human skeletal muscle gene expression
National Aeronautics and Space Administration —
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic... -
Federal
Microarray Analysis of Space-flown Murine Thymus Tissue
National Aeronautics and Space Administration —
Microarray Analysis of Space-flown Murine Thymus Tissue Reveals Changes in Gene Expression Regulating Stress and Glucocorticoid Receptors. We used microarrays to... -
Federal
Exposure of zebrafish larvae to relative microgravity between 5-6 days post-fertilization
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special... -
Federal
Eruca sativa Rocket Science RNA-seq
National Aeronautics and Space Administration —
In the Rocket Science citizen science project Eruca sativa (salad rocket) seeds stored for six months on board of the International Space Station caused delayed crop... -
Federal
Effects of bedrest and hypoxia on human skeletal muscle miRNA expression
National Aeronautics and Space Administration —
The present study concerns the effects of 21 days of sustained recumbence (bedrest) and hypoxia alone and in combination on skeletal muscle microRNA expression. 14... -
Federal
Effect of a 91 day long stay in weightlessness on the International Space Station on mouse skin physiology
National Aeronautics and Space Administration —
Comparative gene expression in skin between mice maintained in microgravity (0g) and normogravity (1g) environment. Six male C57Bl/J10 mice were housed for 91 days in... -
Federal
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU) microgravity in mice: brain transcriptomic and epigenomic data
National Aeronautics and Space Administration —
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose... -
Federal
Proton irradiation augments the reduction in tumor progression observed with advanced age
National Aeronautics and Space Administration —
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have... -
Federal
Methylome Analysis of Arabidopsis Seedlings Exposed to Microgravity
National Aeronautics and Space Administration —
DNA methylation is a very important kind of epigenetic modification and participates in many biological functions. Although many previous studies have addressed... -
Federal
Dynamic gene expression response to altered gravity in human T cells (parabolic flight)
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
The Heat-Inducible Transcription Factor HsfA2 Enhances Anoxia Tolerance in Arabidopsis
National Aeronautics and Space Administration —
Anoxia induces several heat shock proteins and a heat pre-treatment can acclimatize Arabidopsis seedlings to a subsequent anoxic treatment. In this work we analyzed... -
Federal
Effects of a Closed Space Environment on Gene Expression in Hair Follicles of Astronauts in the International Space Station
National Aeronautics and Space Administration —
In recent times long-term stay has become a common occurrence in the International Space Station (ISS). However adaptation to the space environment can sometimes pose... -
Federal
Zebrafish larvae submitted to simulated microgravity on a clinostat (CLINO) at 5dpf for one day
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors specifically simulation of microgravity with a special... -
Federal
Characterization of Epigenetic Regulation in an Extraterrestrial Environment: The Arabidopsis Spaceflight Methylome [RNA-seq]
National Aeronautics and Space Administration —
When germinated and grown on-board the ISS (International Space Station) plant do not exhibit abnormal structures but they do have altered growth habits and this... -
Federal
Global gene expression profiling of radiation-induced rat mammary carcinomas
National Aeronautics and Space Administration —
To investigate gene expression patterns in rat mammary carcinomas induced by ionizing radiation. Gene expression patterns were analyzed in radiation-induced rat... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Plasma
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Dynamic gene expression response to altered gravity in human T cells (sounding rocket flight)
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
HARV replication of the BRIC-23 Bacillus subtilis spaceflight
National Aeronautics and Space Administration —
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This...
63 datasets found