DOMINE is a database of known and predicted protein ___domain interactions (or ___domain-___domain interactions).[1] It contains interactions observed in PDB crystal structures, and those predicted by several computational approaches. DOMINE uses Pfam HMM profiles for protein ___domain definitions. The DOMINE database contains 26,219 interactions among 5,410 domains), which includes 6,634 known interactions inferred from PDB structure data.
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| Content | |
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| Description | comprehensive collection of known and predicted ___domain-___domain interactions. |
| Contact | |
| Research center | National Institute of Environmental Health Sciences, National Institutes of Health |
| Laboratory | Systems Biology |
| Primary citation | Yellaboina et al. (2011)[1] |
| Release date | 2010 |
| Access | |
| Website | https://manticore.niehs.nih.gov/domine |
References
edit- ^ a b Yellaboina; et al. (Jan 2011). "DOMINE: a comprehensive collection of known and predicted ___domain-___domain interactions". Nucleic Acids Res. 39 (Database issue). England: D730-5. doi:10.1093/nar/gkq1229. PMC 3013741. PMID 21113022.