Draft:Castor (eClinical Solution)


Castor
Company typePrivate
IndustryClinical trial software
Founded2012
FounderDerk Arts
Headquarters
Amsterdam; New York City
,
Netherlands; United States

Castor is a Dutch software company that develops tools for electronic data capture (EDC) used in clinical trials and other clinical research.[1] The platform has been described in independent coverage as supporting eCRF design, randomisation in randomized controlled trials, ePRO/eCOA, eConsent, and features used in decentralized or hybrid studies.[1][2]

History

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Castor was founded in the Netherlands in 2012 by physician–researcher Derk Arts.[1] In 2020, Forbes reported the company’s US$12 million Series A funding in the context of COVID-19 research use cases.[3]

Software and services

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Independent sources describe Castor as an EDC/CDMS with ePRO/eCOA and eConsent modules, and public APIs used to integrate real world data (RWD).[1][4] A 2022 CIO.com feature profiled Castor among Dutch health-technology firms building software for clinical research.[2]

Market analysis

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Industry analyst Everest Group has included Castor in multiple PEAK Matrix® assessments. In 2024, Castor appeared among the “Major Contenders” in the Life Sciences Electronic Data Capture (EDC) Products PEAK Matrix (20 vendors evaluated).[5][6] In 2023, Everest’s Decentralized Clinical Trial Platforms PEAK Matrix also listed Castor; public materials describe provider tiers and the evaluated vendors.[7][8]

Use in published research

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Peer-reviewed protocols and reports in multiple specialties name “Castor” in their methods:

  • A randomized trial in Nature Medicine reports patient questionnaires delivered via Castor EDC in a heart-failure digital-consult study.[9]
  • The HORIZON-IC multicentre RCT protocol in BMJ Open specifies randomization and questionnaires using Castor EDC.[10]
  • The OPTIMA-BP protocol in Open Heart (BMJ) describes repeated surveys and data entry via Castor EDC.[11]
  • A multinational registry protocol in Head & Face Medicine states the database was built on the “Castor Electronic Data Capture System (Castor EDC)”.[12]

During the COVID-19 pandemic, the World Health Organization acknowledged “Castor EDC” among organizations providing support to the Solidarity Trial Vaccines platform.[13]

Organization

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The company operates in the Netherlands as Ciwit B.V. and in the United States as Castor Research, Inc..[14][15]

See also

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References

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  1. ^ a b c d Hall, Christine (14 July 2021). "Castor, a clinical-trial process company, raises $45M to create more human-centered research". TechCrunch. Retrieved 11 August 2025.
  2. ^ a b Butcher, Melanie (26 June 2022). "4 exciting Dutch healthcare technology companies to watch". CIO.com. Retrieved 11 August 2025.
  3. ^ Jennings, Katie (19 August 2020). "This Big Data Startup Raised $12 Million To Speed Up Clinical Trials For Coronavirus Research". Forbes. Retrieved 11 August 2025.
  4. ^ van Linschoten, Reinier C. A.; Knijnenburg, Sebastiaan L.; West, Rachel L.; van Noord, Desirée (20 October 2023). "CastorEDC API: A Python package for managing real-world data in Castor Electronic Data Capture". Journal of Open Research Software. 11 (1): 12. doi:10.5334/jors.436.
  5. ^ Life Sciences Electronic Data Capture (EDC) Products – PEAK Matrix Assessment 2024 (Report). Everest Group. 3 September 2024. Retrieved 11 August 2025.
  6. ^ "Life Sciences EDC Products PEAK Matrix® 2024 – Focus on Oracle (licensed copy showing full vendor list)" (PDF). Everest Group. October 2024. Retrieved 11 August 2025.
  7. ^ "Decentralized Clinical Trial Platforms – PEAK Matrix® Assessment". Everest Group. 2023. Retrieved 11 August 2025.
  8. ^ "Decentralized Clinical Trial Platforms – PEAK Matrix® Assessment 2023 (licensed copy)" (PDF). Everest Group. 2023. Retrieved 11 August 2025.
  9. ^ Man, Jelle P.; Koole, Maarten A. C.; Meregalli, Paola G.; Handoko, M. Louis; Stienen, Susan; De Lange, Frederik J.; Winter, Michiel M.; Schijven, Marlies P.; Kok, Wouter E. M.; Kuipers, Dorianne I.; Van Der Harst, Pim; Asselbergs, Folkert W.; Zwinderman, Aeilko H.; Dijkgraaf, Marcel G. W.; Chamuleau, Steven A. J.; Schuuring, Mark J. (2024). "Digital consults in heart failure care: a randomized controlled trial" (PDF). Nature Medicine. 30 (10): 2907–2913. doi:10.1038/s41591-024-03238-6. PMC 11485254. PMID 39217271. Retrieved 11 August 2025.
  10. ^ Vlake, Johan Hendrik; Van Bommel, Jasper; Wils, Evert-Jan; Korevaar, Tim IM; Taccone, Fabio; Schut, Anna FC; Elderman, Jan H.; Labout, Joost AM; Raben, Adrienne MTJ; Dijkstra, Annemieke; Achterberg, Sefanja; Jurriens, Amber L.; Van Mol, Margo MC; Gommers, Diederik; Van Genderen, Michel E. (2022). "Effect of intensive care unit–specific virtual reality (ICU-VR) to improve psychological well-being in ICU survivors: study protocol for an international, multicentre, randomized controlled trial — the HORIZON-IC study". BMJ Open. 12 (9): e061876. doi:10.1136/bmjopen-2022-061876. PMC 9490570. PMID 36127077. Retrieved 11 August 2025.{{cite journal}}: CS1 maint: article number as page number (link)
  11. ^ McCallum, L.; Lip, S.; Rostron, M.; Hanna, R.; Bin Pg Md Salimin N; Nichol, S.; Padmanabhan, S. (2024). "OPTIMA-BP: protocol for a randomised parallel group study comparing a web-based education portal plus home blood pressure monitoring versus monitoring alone". Open Heart. 11 (1): e002535. doi:10.1136/openhrt-2023-002535. PMC 10910568. PMID 38429056.{{cite journal}}: CS1 maint: article number as page number (link)
  12. ^ Oechsle, A. L.; Wiechers, C.; Abadie, V.; Abel, F.; Breugem, C.; Poets, C. F. (2023). "International registry for Robin sequence: protocol and database design". Head & Face Medicine. 19 (1): 20. doi:10.1186/s13005-023-00364-3. PMC 10199645. PMID 37210548.
  13. ^ "WHO statement on Solidarity Trial Vaccines". World Health Organization. 26 October 2021. Retrieved 11 August 2025.
  14. ^ "Ciwit B.V." OpenCorporates. Retrieved 11 August 2025.
  15. ^ "Castor Research Inc. Company Profile". Dun & Bradstreet. Retrieved 11 August 2025.
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