User:SharkNote458/Temperature-sensitive mutant/Paradox122 Peer Review

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General info

Whose work are you reviewing?

SharkNote458

Link to draft you're reviewing

Link to the current version of the article (if it exists)

Temperature-sensitive mutant

Evaluate the drafted changes

I think this sentence of the mechanism section could be made more clear, and it also is a run on sentence: These mutations are usually recessive in diploid organisms. Temperature sensitive mutants arrange a reversible mechanism and are able to reduce particular gene products at varying stages of growth and are easily done by changing the temperature of growth.

In the Use in Research section, under examples, the following sentence is unclear as to what they mean by "buds": In the late 1970s, the Saccharomyces cerevisiae secretory pathway, essential for viability of the cell and for growth of new buds, was dissected using temperature-sensitive mutants, resulting in the identification of twenty-three essential genes.

Another example that could be added to the page is C. elegans. This model often uses temperature sensitive mutants, and experiments at different temperatures, to determine mechanisms of genes of interest.

Overall: the article flowed well, was unbiased and succeeded in staying on topic. Other than the examples that I previously mentioned, the language seems to be clear, concise, and easy for laymen to understand. The links worked, and referenced material that helped support the arguments.