Wikipedia:Reference desk/Archives/Science/2025 July 26

Science desk
< July 25	<< Jun | July | Aug >>	July 27 >

Welcome to the Wikipedia Science Reference Desk Archives
The page you are currently viewing is a transcluded archive page. While you can leave answers for any questions shown below, please ask new questions on one of the current reference desk pages.

July 26

GcMAF

Can I post the following new information on the GcMAF page based on Wikipedia posting rules? This corrects a glaring omission on this page? It's been so long since I posted that I have forgotten all the rules and need help. I don't want to start a edit war which is common on this page since there are individuals who want the content on this page to remain negative although the science has moved on and is becoming positive. I just want to correct the record on GcMAF. I have outlined a potential post below. Any recommended wording change or reduced content that just says GcMAF successfully completed a Phase 1 Study would be OK. There is content on the web that says that GcMAF has not been studies for safety and this proves there is false narrative that needs correcting. Thanks for your analysis.

COMPLETED FDA REGISTERED PHASE 1 CLINICAL TRIAL IN ISRAEL

In May 2017 the Sheba Hospital in Israel successfully completed a cancer-related GcMAF (under the name EF-022) FDA registered Phase 1 Clinical Trial. Results for Part 1 of this trial were presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held November 5-9, 2015 in Boston, Massachusetts.

In the Part 1, Phase 1 Clinical Trial GcMAF was found to have an acceptable safety profile and resulted in cancer related disease stabilization in 42% of trial patients. Pharmacodynamics markers suggest a reduction of Tregs and increase of the M1/M2 ratio.

https://mct.aacrjournals.org/content/14/12_Supplement_2/B30

https://clinicaltrials.gov/study/NCT02052492 PageMaster (talk) 01:12, 26 July 2025 (UTC)[reply]

The reference desk is not equipped to answer this question. Try the talk page of the article, Talk:GcMAF, but perhaps read the section Talk:GcMAF § Efranat edits first, since this seems to be about the same clinical trial.  ​‑‑Lambiam 05:06, 26 July 2025 (UTC)[reply]

PS. I see you posted over seven years ago on that talk page, in that very section, so why did you come here now?  ​‑‑Lambiam 05:10, 26 July 2025 (UTC)[reply]

cytoplasmic streaming

In today's picture of the day (first video in cytoplasmic streaming) is the video at real time or is it sped up or down? (I didn't know where to ask this, so here seemed the best place.) -- SGBailey (talk) 05:10, 26 July 2025 (UTC)[reply]

There is an implicit rule^{[citation needed]} in science that when media of an observation is altered in any non-obvious way, the alteration is described together with any presentation of the media. This would include altering the time rate of a video. No alteration is mentioned at commons:File:Cytoplasmic streaming.webm.  ​‑‑Lambiam 05:24, 26 July 2025 (UTC)[reply]

I guess the article could probably benefit from some information about the range of speeds for cytoplasmic streaming. The length of onion epidermal cells seems to be in the 0.2 to 0.4mm range, or thereabouts, so the video being at real time doesn't seem unreasonable. Streaming in slime molds can be much faster than that. I didn't realize until quite recently that cytoplasmic streaming is used in modeling e.g. "Revealing the Dark Threads of the Cosmic Web". Sean.hoyland (talk) 06:41, 26 July 2025 (UTC)[reply]